Osteoclasts
Breaking Down and Balancing Bone
Osteoclasts are large, multinucleated cells responsible for breaking down and resorbing bone tissue during remodeling, growth, and repair. They attach to bone surfaces and secrete acids and enzymes that dissolve both the mineral and organic components of bone matrix, creating resorption pits. Osteoclasts work in balance with osteoblasts to maintain bone density and shape throughout life.
Art by Alexandra Banbanaste. Set in motion by Dr. Emanuele Petretto. Words by Dr. Christy Kestner. Project Coordinator: Dr. Masia Maksymowicz-Trivedi. Series Director: Dr. Radhika Patnala
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